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Prostate Cancer Clinical Trials


Learn More About Prostate Cancer

For general information on prostate cancer (including risk factors, symptoms, diagnosis, and treatment) visit the Cancer Council’s website:

General Enquiries

For general questions about trial availability, eligibility, or the referral process, please contact us using the form below. Our team will respond as soon as possible.

Protocol NumberCancer TypeStudy NameInterventionMechanism of ActionRecruitment StatusSponsorClinicalTrials.gov IDClick to Enquire
AWT020-001Castrate-Resistant Prostate CancerA Phase 1/2, First-in-human, Open-label Study of Single-agent AWT020 in Patients With Progressive Locally Advanced or Metastatic CancerImmunotherapyAnti-PD1 IL-2 BiTE.Open - RecruitingAnwita BiosciencesNCT06092580Enquire Now
HRS-5041-103Castrate-Resistant Prostate CancerA Phase I, Open-label, Multi-Center, Non-Randomized Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of HRS-5041 in Subjects With Metastatic Castration-resistant Prostate CancerTargetedAR-PROTAC molecule - AR degraderOpen - RecruitingAtridia Pty LtdNCT06830850Enquire Now
PSMA-007-001Castrate-Resistant Prostate CancerA Phase 1, Open-Label, Multicenter Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate CancerImmunotherapyInhibitor of the pH-sensing G-protein-coupled receptor 65Open - RecruitingJanux TherapeuticsNCT05519449Enquire Now
DM002001Castrate-Resistant Prostate CancerA Phase I, Multicentre, Open-label, First-in-Human, Dose Escalation and Expansion Study of DM002 in Patients With Advanced Solid TumorsAntibody Drug ConjugateADC targeting MUC1 and HER3Open - RecruitingXadcera Biopharmaceutical (Suzhou) Co., Ltd.NCT06751329Enquire Now
PTT-4256-01Castrate-Resistant Prostate CancerA Modular, Open Label, Dose Finding, Phase 1/2 Clinical Trial in Patients With Solid Tumours to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of PTT-4256.ImmunotherapyADC targeting a tissue factor.Open - RecruitingPathios Therapeutics Pty LtdNCT06634849Enquire Now
ADCE-T02-01Castrate-Resistant Prostate CancerFirst-in-Human, Phase 1 Study of ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Advanced Solid TumorsAntibody Drug ConjugateIntratumoral (IT) injection. PC7A nanoparticles loaded with cGAMP. Stimulator of interferon genes.Open - RecruitingAdcendo ApSNCT06597721Enquire Now