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Oesophageal Cancer Clinical Trials


Learn More About Oesophageal Cancer

For general information on oesophageal cancer (including risk factors, symptoms, diagnosis, and treatment) visit the Cancer Council’s website:

General Enquiries

For general questions about trial availability, eligibility, or the referral process, please contact us using the form below. Our team will respond as soon as possible.

Protocol NumberCancer TypeStudy NameInterventionMechanism of ActionRecruitment StatusSponsorClinical.Trials.gov IDClick to Enquire
MTX-TROP2-302Oesophageal CancerMYE Symphony: A Phase 1, Open-Label, First-in-Human, Dose Escalation Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of MT-302 in Adults With Advanced or Metastatic Epithelial TumorsImmunotherapyTROP2 targeting. Low volume disease only.ClosedMyeloid TherapeuticsNCT05969041Enquire Now
ADCE-T02-01Oesophageal CancerFirst-in-Human, Phase 1 Study of ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Advanced Solid TumorsAntibody Drug ConjugateADC targeting a tissue factor.Open - RecruitingAdcendo ApSNCT06597721Enquire Now
SSGJ-709-101Oesophageal CancerA Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Anti-tumor Activity of SSGJ-709 in Patients With Advanced Malignant TumorsImmunotherapyAnti-PD-1 and anti-LAG-3 bispecific antibodyOpen - RecruitingShenyang Sunshine Pharmaceutical Co., LTD.NCT07016490Enquire Now
AMT-116-01Oesophageal CancerFirst-in-Human, Phase 1 Study of AMT-116 in Patients With Advanced Solid TumorsAntibody Drug ConjugateAnti-CD44v9 Antibody-Drug ConjugateOpen - RecruitingMultitude Therapeutics Inc.NCT05725291Enquire Now
AMT-253-01Oesophageal CancerFirst-in-Human, Phase 1 Study of AMT-253, in Patients With Advanced Solid TumorsAntibody Drug ConjugateAnti-MUC18Open - RecruitingMultitude Therapeutics (Australia) Pty LtdNCT05906862Enquire Now
HMBD-001-103Oesophageal CancerA Phase 1b Study to Evaluate HMBD-001 in Combination With Docetaxel With or Without Cetuximab in Participants With Advanced Squamous Non-Small Cell Lung Cancers, and HMBD-001 in Combination With Cetuximab in Participants With Advanced Squamous Cell CancersTargetedHumanized IgG1 anti-HER3 monoclonal antibody + Combo treatment for squamous HER3 Mutation.Open - RecruitingHummingbird BioscienceNCT05910827Enquire Now
CP-IVX001Oesophageal CancerA Phase 1 Open-label, Non-randomized, Multi-cohort Clinical Study of Intratumoral IVX037 in Patients With Advanced or Metastatic Solid TumoursInjectable LesionsOvarian, Gastric and CRC only. Must have Injectable lesions. Intratumoral injection. Live EchoVirus, No GMO component.Open - RecruitingImmVirx PtyLtdNCT05427487Enquire Now
ON-5001Oesophageal CancerA Phase 1 Dose-Escalation and Expansion Study of Intratumorally Administered ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and LymphomasInjectable LesionsIntratumoral (IT) injection. PC7A nanoparticles loaded with cGAMP. Stimulator of interferon genes.ClosedOncoNano Medicine, Inc.NCT06022029Enquire Now